Vanilloid Receptors

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Vanilloid Receptors

CBD directly interacts with various ion channels to confer a therapeutic effect. CBD, for example, binds to TRPV1 receptors, which also function as ion channels. TRPV1 is known to mediate pain perception, inflammation and body temperature. TRPV is the technical abbreviation for “transient receptor potential cation channel subfamily V.” TRPV1 is one of several dozen TRP (pronounced “trip”) receptor variants … Read More

CBD as an allosteric modulator

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allosteric modulator

Allosteric Modulator Australian scientists report that CBD acts as a “positive allosteric modulator” of the GABA-A receptor. In other words, CBD interacts with the GABA-A receptor in a way that enhances the receptor’s binding affinity for its principal endogenous agonist, gamma-Aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. The sedating effects of Valium … Read More

CBD Reuptake Inhibitor – Hitching a Ride with a FABP

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Tourettes Syndrome

CBD Reuptake Inhibitor How does CBD, an exogenous plant compound, get inside a human cell to bind to a nuclear receptor? First it has to pass through the cell membrane by hitching a ride with a fatty acid binding protein (FABP), which chaperones various lipid molecules into the cell’s interior. These intracellular transport molecules also escort tetrahydrocannabinol (THC) and the … Read More

Industrial Hemp Revival

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Industrial Hemp

Joy Beckerman, president of Hemp Ace International, a Seattle-based consulting firm, teaches a class for law students on “The Curious Legal Status of CBD and Industrial Hemp-Derived Cannabinoids.” An industrial hemp entrepreneur and advocate for the past 25 years, Beckerman recognizes that cannabidiol has played a key role in jump-starting the creation of new infrastructure for hemp’s vast oilseed and … Read More

New Third Party Lab Results!

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Lab Results

New Third Party Lab Results! Cannabidiol is a highly debated product in the current US political and medical world, and everyone’s experience with ANY cannabinoid or hemp product can be different. Each of us has a unique brain with unique brain receptors and unique tolerances. That being said we are confident and stand behind that fact that our products are … Read More

Anxiety, Depression and treating it with Cannabidiol

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Anxiety and depression are two of the most common mental health concerns in the world today. In fact, the chances are fairly good that you, the reader, have dealt with (or will deal with) a clinically-diagnosable level of anxiety of depression at some point during your lifetime—whether it’s lasting or temporary. According to statistics released by the Anxiety and Depression … Read More

Cardiovascular Issues and How CBD Could Help

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Cardiovascular Issues

Heart disease is—and has been for decades—the leading cause of death in the United States. As many as a quarter of the deaths in the country can be attributed to heart disease, particularly in the case of males. Often, those dealing with known heart conditions are given a directive to improve diet and exercise and are prescribed some sort of … Read More

Tourette’s Syndrome and the Possible Cannabidiol Answer

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Tourettes Syndrome

When you hear the words “Tourette’s syndrome,” chances are you have a particular image in mind: a young child, perhaps thrashing about, swearing at his parents and saying unspeakable things in public. While it’s certainly the most famous and dramatic portrayal of the condition, Tourette’s syndrome can affect an individual of any age, and is usually more subdued, involving a … Read More

Kick (cigarette) butt with CBD oil

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quitting cigarettes

“That’s it, I’m quitting for good!” Thousands have said it, have declared being finished with smoking cigarettes forever, but not all manage to pull through. The mere mention of quitting cigarettes can bring a sympathetic grimace to any face, as we all know that nicotine cravings are notoriously tough to beat. Fortunately for those seeking to kick the butt completely, … Read More